NUTRITIONAL MANAGEMENT OF PANCREATIC FISTULA POST SPLENECTOMY DURING CYTOREDUCTIVE SURGERY FOR OVARIAN CANCER

Abstract

This study aimed to evaluate the safety and efficacy of a specified nutritional planning after a pancreatic fistula (PF) diagnosis (1). Patients with clinical or laboratory diagnosis of PF after cytoreductive surgery (CRS) for ovarian cancer at the Fondazione Policlinico “A. Gemelli” – IRCCS in Rome, were enrolled in this study. Each patient started parenteral nutrition from the 1st postoperative day (POD) and a specific diet with increasing food texture and caloric intake (mean from 600 to 1500 kcal) was decided case-by-case, according to surgeon decision. Here we present the first data from the first ten patients enrolled. Data are presented as median (IQR). Ten patients [age: 63 (49-66), BMI: 24.2 (20.4-25.0)] were enrolled between January and June 2020. The median of starting oral nutrition was 4 days [median: 4 (3-8)]. Both the abdominal drainages output and amylases level were reduced in all patients. Early oral feeding, with increasing food texture and calories, seems to be a safe and efficint procedure in nutritional management of PF, aiming to reduce PF output. Therefore, a personalized early refeeding should be encouraged, aiming to reduce the PF-related complications.