Abstract
Man evolved as a wild animal and his nutritional biology was adapted to wild plants and animals. That diets have been modified by trade is illustrated from the author's experience in Uganda where dramatic differences occur in the diets in the North and South of the country. Internationally, the incidence and pattern both of cardiovascular disease and cancer caries with the ecology of the regions. What is seen in miniature in Uganda is to be seen enlarged upon a world scale. In the course of agriculture we have changed the balance of nutrients offered by wild plants and animals. In particular we have substituted storage fat for structural fat whilst also changing our diet in the direction of a high refined carbohydrate food structure.
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