Abstract
Here we present an extensive narrative review of the broadly understood modifications to the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was analyzed, combining PCOS entries with causes, diseases, diet supplementation, lifestyle, physical activity, and use of herbs. The metabolic pathways leading to disturbances in lipid, carbohydrate, and hormonal metabolism in targeted patients are described. The article refers to sleep disorders, changes in mental health parameters, and causes of oxidative stress and inflammation. These conditions consistently lead to the occurrence of severe diseases in patients suffering from diabetes, the fatty degeneration of internal organs, infertility, atherosclerosis, cardiovascular diseases, dysbiosis, and cancer. The modification of lifestyles, diet patterns and proper selection of nutrients, pharmacological and natural supplementation in the form of herbs, and physical activity have been proposed. The progress and consequences of PCOS are largely modifiable and depend on the patient’s approach, although we have to take into account also the genetic determinants.
Highlights
The analysis of metabolic symptoms occurring in the course of polycystic ovary syndrome (PCOS) points to the need for a multidirectional therapeutic approach
The metabolic pathways leading to the abnormalities are presented, which requires focusing on the improvement of parameters related to fertility, hirsutism, the occurrence of carbohydrate-lipid disturbances and the reduction of insulin resistance
It has been shown that significant improvement of these parameters depends on modifiable factors related to the improvement of lifestyle, the introduction of a diet, especially a low-calorie diet with reduced glycemic index (GI), normalization of sleep and the introduction of daily physical activity
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. The definition of PCOS changed in 2003, when representatives of the European Society of Human Reproduction and American Society of Reproductive Medicine met in Rotterdam, The Netherlands. It is defined as a heterogeneous group with different phenotypes, which pose challenges in its treatment [2]. The therapeutic approaches aimed at using anti-inflammatory remedies supporting anticancer anticancer therapy are crucial. They can helpininsupplementing inactivating theand cascade of the deteriorattherapy are crucial. These, better faster recovery, and the improvement of the ment of the Through patients’ quality of lifesurvival, can be achieved.
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