Abstract
The innovations in the medical science and development of new biotechnology medicines changed significantly the course of the human immune-deficiency virus (HIV) infection toward a chronic condition. Along HAART, habits in nutrition place an important role in the improvement of the health status of people living with HIV. Proper diet and nutrition may enhance the adherence and concordance to prescribed therapy and its effectiveness, to reduce the risk of adverse drug events and to boost the immune function. In the resent years a tendency towards increased food supplements consumption is observed, especially in patients with chronic diseases. There is a risk of possible interactions between selected dietary supplements with the antiretroviral medicines which may result in decrease of the drug concentrations in the blood plasma and subsequent decreased therapeutic effect and increased risk of viral resistance. Still there are gaps in respect with such information in the guidelines and recommendations for treatment, monitoring and nutrition in HIV. More studies are needed to fully evaluate such interactions and to put recommendations both for the healthcare professionals and for the people living with HIV for their use in order not to compromise HAART and to maintain the desirable therapeutic outcome.
Highlights
The innovations in the medical science and development of new biotechnology medicines changed significantly the course of the human immune-deficiency virus (HIV) infection towards a chronic condition
One of Nutrition and HIV/AIDS - Implication for Treatment, Prevention and Cure the main concerns in terms of nutrition habits, especially food supplement intake, is related to possible interactions with the antiretroviral medicines which may result in decrease of the drug concentrations in the blood plasma and subsequent decreased therapeutic effect and increased risk of viral resistance [2]
The innovations in the medical science and development of new biotechnology medicines changed the course of the human immune-deficiency virus (HIV) infection towards a chronic condition and increased significantly the life expectance
Summary
The innovations in the medical science and development of new biotechnology medicines changed significantly the course of the human immune-deficiency virus (HIV) infection towards a chronic condition. One of Nutrition and HIV/AIDS - Implication for Treatment, Prevention and Cure the main concerns in terms of nutrition habits, especially food supplement intake, is related to possible interactions with the antiretroviral medicines which may result in decrease of the drug concentrations in the blood plasma and subsequent decreased therapeutic effect and increased risk of viral resistance [2]. In this respect there are still gaps of scientific evidence for the antiretroviral drug-to-supplement interactions and only a few dietary supplements (i.e., Ca, Mg, Fe supplements) have been evaluated in combination with the currently available on the pharmaceutical market antiretroviral medicines [3, 4]. People living with HIV should be willing to communicate with their healthcare providers any administration of dietary supplements and special nutrition regimes in order to optimize their intake in compliance with the prescribed HAART and to avoid possible undesirable interactions
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