Abstract
This study aimed to investigate the nutricosmetic effect of Asparagus officinalis extracts. The tip and spear of A. officinalis were successively extracted with 95% ethanol. The rutin, phenolic, and flavonoid contents of A. officinalis extracts were investigated. The antioxidant activities were determined by 2,2-azinobis (3-ethylbenzothiazoline-6-sulphonic acid) and a ferric reducing antioxidant power assay. Matrix metalloproteinase-1 (MMP-1), elastase, and hyaluronidase inhibition were determined by in vitro enzyme reaction assay. The cytotoxicity was analyzed on peripheral blood mononuclear cellss. Findings revealed that drying temperature and drying duration had significant effects on the chemical composition and biological activity of A. officinalis extract. A. officinalis tips dried at 50 °C for 24 h contained the (significantly) highest flavonoid and rutin content. The most potent extract was from A. officinalis spears since it possessed the (significantly) highest MMP-1, elastase, and hyaluronidase inhibition rates of 83.4 ± 1.5%, 70.4 ± 4.1%, and 75.2 ± 1.0%, respectively. Interestingly, at the same concentration, the A. officinalis spear extract was more potent in MMP-1 inhibition than oleanolic acid and epigallocatechin gallate, the well-known natural MMP-1 inhibitors. The results show that A. officinalis extract is an attractive source of natural anti-skin-wrinkle ingredients.
Highlights
This study aimed to investigate the nutricosmetic effect of Asparagus officinalis extracts
The spear part of A. officinalis was selected as the plant material, and the drying temperature was set to 50 °C
The results showed that a drying duration longer than 24 h was unnecessary since the A. officinalis material was completely dried at 24 h
Summary
This study aimed to investigate the nutricosmetic effect of Asparagus officinalis extracts. Findings revealed that drying temperature and drying duration had significant effects on the chemical composition and biological activity of A. officinalis extract. A. officinalis stalks that are smaller in size are excluded and separately sold at a lower price These by-products and lower grade of A. officinalis are reported to contain similar phytochemicals[3], their commercial value is not high. The anti-wrinkle activities and beneficial effects of A. officinalis extract on skin ageing have. This study is the first to report on the nutricosmetic effect of A. officinalis extract in relation to matrix metalloproteinase-1 inhibition. Since the drying process is reported to influence both the chemical composition and biological activity of A. officinalis[8], the effects of drying temperature and drying duration on the chemical composition and nutricosmetic activity were investigated
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