Abstract
气性坏疽是由梭状芽孢杆菌侵入伤口引起的一种严重的特异性感染[1].梭状芽孢杆菌广泛存在于泥土和人畜粪便中.地震后,伤者长时间掩埋于废墟下,大量失水、失血、伤口大片组织坏死、深层肌肉损毁极容易发生气性坏疽,气性坏疽杆菌在伤口的肌肉中繁殖,产生多种酶和毒素,引起肌糖原发酵产生气体,分解蛋白质产生硫化氢,气体在组织间隙不断增多,使伤口局部胀裂样疼痛,进行性肿胀[2].伤口有腐肉样气味,全身出现毒血症,某些毒素并可直接侵犯心、肝、肾等发生局灶性坏死,而使创伤、复合性骨折、挫伤或撕裂伤变得复杂化[3].其发病急,症状重,可迅速导致死亡或致残.我科2008年5月收治2例在汶川地震中受伤并发气性坏疽患者,经过精心治疗和护理,患者痊愈,未发生交叉感染,现报道如下。
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