Abstract

Objective To explore the nursing effect of Sandostatin combined with Losec in the treatment of post-hepatitis cirrhosis complicated with upper gastrointestinal bleeding. Methods 88 patients with post-hepatitis cirrhosis and upper gastrointestinal bleeding treated at our hospital from October, 2017 to October, 2018 were randomly divided into a control group and a study group. Both groups were treated with Sandostatin and Losec; the control group received routine nursing, and the study group nursing targeting at diet, psychology, medication, daily life, and discharge guidance. The nutritional indicators such as depression, anxiety score, total protein (TP), plasma albumin (ALB), and body mass index (BMI) as well as bleeding frequency, bleeding rate, average hemostasis time, and hemostasis efficiency were compared between the two groups. Results The post-discharge depression score and anxiety score were (41.7±6.6) and (42.3±11.2) in the study group, and were (48.4±5.5) and (47.6±9.1) in the control group (both P<0.05). After 2 weeks of treatment, TP was (59.5±6.7) g/L, ALB was (38.8±5.2) g/L, BMI was (22.9±3.8) kg/m2, and after 2 weeks of treatment, the control group was (52.8±6.7) g/m2. Two weeks after the treatment, the TP, ALB, and BMI were (59.5±6.7) g/L, (38.8±5.2) g/L, and (22.9±3.8) kg/m2 in the study group, and were (52.8±5.9) g/L, (36.4±4.8) g/L, and (21.8±3.7) kg/m2 in the control group (all P<0.05). The number of bleeding, the bleeding rate, the average time of hemostasis, and the effective rate of hemostasis and were (1.1±0.2), 6.8%, (13.6±5.5) h, and 95.5% in the study group, and were (2.5±0.8), 22.7%, (32.3±7.7) h, and 86.4% in the control group (all P<0.05). Conclusion Targeted nursing for patients with post-hepatitis cirrhosis and upper gastrointestinal bleeding treated by Sandostatin and Losec is remarkably effecttive, so it is worth being clinically generalized. Key words: Sandostatin; Losec; Hepatitis; Liver cirrhosis complicated with upper gastrointestinal bleeding; Nutrient levels

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