Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report

Abstract

Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a systemic disease associated with high morbidity and mortality rates, caused by dysregulation of the alternative complement pathway, leading to uncontrolled complement activation resulting in thrombotic microangiopathy. In this case it’s reported patient care management of a P-aHUS patient which developed in postpartum period with renal failure, anasarca edema, hypertension and important laboratory signs of the syndrome. Patient was effectively treated by hemodialysis and eculizumab therapy, which controls complement activation and discharged without signs of hemolysis. The patient was discharged to home from the hospital after 42 days. At follow-up 2 weeks after discharge, all signs and symptoms of renal failure had resolved. The patient has not had any inpatient readmissions to the hospital to date. There are no case report in P-aHUS nursing care. Discussion of this case contributes the literature describing nursing interventions associated with caring for patients with P-aHUS.