Abstract
Intracranial aneurysm (IAs) is a frequently localized cerebral vascular disorder of an overall prevalence of 5-8% [Cebral (2013)]. Subarachnoid hemorrhage (SAH) caused by IAs rupture is one of the major causes of mortality and morbidity in the modern world. Local hemodynamic characteristics played important roles in the rupture of IAs and has been studied extensively from different perspectives [Liu (2015); Brinjikji (2017)]. However, the influence of progressive cerebral stenosis on the hemodynamic of the distal cerebral aneurysm is yet to be further investigated. In this study, a set of patient-specific computational fluid dynamics (CFD) simulations were performed to investigate the impact of internal carotid artery (ICA) stenosis growing on the hemodynamic environments in an anterior communicating artery aneurysm (ACoAA).
Highlights
Intracranial aneurysm (IAs) is a frequently localized cerebral vascular disorder of an overall prevalence of 5-8% [Cebral (2013)]
A jet flow comes from RACA-A1 under no stenosis case gradually shifts toward left with the increased stenosis degree, and the blood flow ejected from LACA-A1 becomes the dominate jet
The overall pressure on the anterior communicating artery aneurysm (ACoAA) dome decreased with the growing of unilateral internal carotid artery (ICA) stenosis
Summary
Intracranial aneurysm (IAs) is a frequently localized cerebral vascular disorder of an overall prevalence of 5-8% [Cebral (2013)]. Subarachnoid hemorrhage (SAH) caused by IAs rupture is one of the major causes of mortality and morbidity in the modern world. Local hemodynamic characteristics played important roles in the rupture of IAs and has been studied extensively from different perspectives [Liu (2015); Brinjikji (2017)]. The influence of progressive cerebral stenosis on the hemodynamic of the distal cerebral aneurysm is yet to be further investigated. A set of patient-specific computational fluid dynamics (CFD) simulations were performed to investigate the impact of internal carotid artery (ICA) stenosis growing on the hemodynamic environments in an anterior communicating artery aneurysm (ACoAA)
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