Abstract
A new computer-aided method to design electrospun, nanofibrous mats was implemented and tested. In this work, the standard nonlinear algebraic model led to the terminal fiber diameter FD being examined in detail. The analysis was performed in terms of numerical feasibility. The study specified the limit value of the axial length scale, parameter χ, that determined valid solutions. The presented approach has vast practical potential (i.e., biomedical applications, air/water purification systems, fire protection and solar industries).
Highlights
Electrospinning (ES) has been one of the most dynamically developing technologies over past decades [1]
This study has investigated the nonlinear algebraic model in terms of numerical feasibility
The identification of the feasible and infeasible regions led to the determination of the proper set of points that satisfied all imposed constraints; the work was focused on constraints imposed on the axial length scale: χ parameter
Summary
Electrospinning (ES) has been one of the most dynamically developing technologies over past decades [1]. ES contributes to the formation of polymeric fibers with a nano-scale diameter, that can mimic extracellular matrix [4]. Thanks to this feature, ES may be considered as a technology suitable for biomedical applications. Dettin and co-authors [5] presented in their work a problem associated with the mechanism of cell– biomaterial adhesion. For this purpose, they characterized electrospun poly-ε-caprolactone (PCL) scaffolds with an increasing concentration of self-assembling peptides (SAPs). Bazzolo and co-authors proposed the use of polycaprolactone electrospun structures in preclinical studies in relation to effective breast cancer therapy [6]. Some recent studies have focused on the use of electrospun materials in the filtration/purification processes [8], the flame retardant sector [9], and the solar industry [10]
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