Numerical analysis of the mechanical behaviour of intact and implanted lumbar functional spinal units: Effects of loading and boundary conditions.

Abstract

The objective of this study was to develop an improved finite element (FE) model of a lumbar functional spinal unit (FSU) and to subsequently analyse the deviations in load transfer owing to implantation. The effects of loading and boundary conditions on load transfer in intact and implanted FSUs and its relationship with the potential risk of vertebral fracture were investigated. The FE models of L1-L5 and L3-L4 FSUs, intact and implanted, were developed using patient-specific CT-scan dataset and segmentation of cortical and cancellous bone regions. The effect of submodelling technique, as compared to artificial boundary conditions, on the elastic behaviour of lumbar spine was examined. Applied forces and moments, corresponding to physiologic movements, were used as loading conditions. Results indicated that the loading and boundary conditions considerably affect stress-strain distributions within a FSU. This study, based on an improved FE model of a vertebra, highlights the importance of using the submodelling technique to adequately evaluate the mechanical behaviour of a FSU. In the intact FSU, strains of 200-400 µε were observed in the cancellous bone of vertebral body and pedicles. High equivalent stresses of 10-25 MPa and 1-5 MPa were generated around the pars interarticularis for cortical and cancellous regions, respectively. Implantation caused reductions of 85%-92% in the range of motion for all movements. Insertion of the intervertebral cage resulted in major deviations in load transfer across a FSU for all movements. The cancellous bone around cage experienced pronounced increase in stresses of 10-15 MPa, which indicated potential risk of failure initiation in the vertebra.