Abstract
While the diagnosis of Addison's disease can be made with some degree of probability in a considerable number of cases, in only a few can it be made with certainty. While perhaps not much can be expected from such treatment as is at present at our command, nevertheless it would be desirable for clinical purposes to possess some trustworthy diagnostic sign. Different observers have recorded the existence of different states of the blood in cases of Addison's disease, although the extreme pallor often present would suggest the existence of anemia. Christomanos<sup>2</sup>records two observations of adrenal disease in which the number of red blood-corpuscles was found increased on repeated examination, although the percentage of hemoglobin was subnormal. One was clinically a classic example of Addison's disease, exhibiting caseous degeneration of the adrenal bodies on post-mortem examination. The other proved to be one of adenocarcinoma involving the adrenal glands. Both
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