Abstract

Diestrous rats were treated with an injection of luteinizing hormone (LH), and their ovaries were examined for mast cell number and stage of degranulation at 2 and 4 hr post-injection. LH tripled the number of medullary mast cells at 2 hr. The source or origin of the additional mast cells is unknown. Comparison of the present results with other studies of rat ovarian mast cell dynamics suggests the occurrence of a reduction in mast cell number in early to mid-proestrus followed by an LH-induced increase in late proestrus.

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