Abstract
AbstractThe biosynthesis of purine and pyrimidine nucleotides takes place overde novosynthetic pathways from small molecules and by salvage pathways from preformed purine or pyrimidine bases or nucleosides. The pathways ofde novosynthesis are the same in animals and microorganisms. Salvage pathways are considerably more energy‐efficient thande novopathways, which require 5 (pyrimidine) or 6 (purine) moles of ATP for each mole of nucleotide produced.
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