Abstract
A convenient motif-searching program has been developed, based on a double correlation algorithm, for analysis of the pulse character of Escherichia coli transcription. Activity in the zone of minimal pause formation (-1,2 bp) is precisely determined. Oligonucleotides (di-, tri- and tetranucleotides) are randomized by their pause-generating activity. 'CATG' and 'CATGC' are detected which coincide with the primary structure of RNA associated with distinctive delays in biologically meaningful situations.
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