Nucleotide Analogues as Antiviral Agents

Abstract

Inhibitors of Viral Nucleic Acid Polymerases. Pyrophosphate Analogues Synthesis of Acyclonucleoside Phosphonates for Evaluation as Antiviral Agents Structural Requirements for Enzymatic Activation of Acyclonucleotide Analogues and the Relationship of Their Mode of Antiherpetic Action Phosphonylmethyl Ethers of Nucleosides and Their Acyclic Analogues Synthesis and Antiviral Activity of Phosphonylmethoxyethyl Derivatives of Purine and Pyrimidine Bases Synthesis and Antiviral Activity of Nucleotide Analogues Bearing the (S)-(3-Hydroxy-2-Phosphonylmethoxy)propyl Moiety Attached to Adenine, Guanine, and Cytosine Design of Inhibitors of Herpes Simplex Virus Thymidine Kinase Nucleotides as Herpesvirus-Specific Inhibitors of Protein Glycosylation Antiviral Activity of the Nucleotide Analogue Ribavirin 5'-Sulfamate Design, Synthesis, and Antiviral Activity of Nucleoside and Nucleotide Analogues Nucleotide Dimers as Anti-HIV Agents Oligonucleotide Analogues as Potential Chemotherapeutic Agents