Abstract
Abstract Eight carbocyclic puromycin analogs, in which the furanosyl ring of puromycin is replaced with a cyclopentyl system, were synthesized. Their minimum degeneration concentration (MDC) was determined against HeLa cells in a tissue culture. The two analogs were found to be remarkably active.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have