Abstract

1. 1. A nucleoprotein fraction (NPF) was isolated by streptomycin precipitation from twelve different chick embryo tissues. 2. 2. Bioassays in tissue culture revealed maximum growth-promoting activity in those NPF's from material containing cartilage. 3. 3. Electrophoretic analyses indicate that the leading peaks of the highly active NPF's are much greater than those of the other NPF's. 4. 4. Ultraviolet analyses of tissue NPF's indicate similar nucleoprotein absorption spectra, while the electrophoretic subfractions of these NPF's exhibit families of curves which are similar and have maxima from 257 mμ to 275 mμ.

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