Abstract
Trialkylsilyl triflates promote the direct nucleophilic reaction of “non-nucleophilic DBU and DBN” with methyl pheophorbide a ( 1) to give substituted chlorin e 6 amides 3 and 4, where the bicyclic bases have undergone ring opening. The reaction most likely results from coordination of trialkylsilyl triflates to the β-ketoester in 1, forming an ion-pair intermediate 6. The adduct 6 is so strongly electron-deficient that it can electrophilically attack the nonbonding nitrogen electron pairs in DBU and DBN.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
