Abstract
Various fluorinated chiral compounds were synthesized using bis(2-methoxyethyl)aminosulfur trifluoride (Deoxofluor) as a nucleophilic fluorinating reagent. Reactions of Deoxofluor ( 1) with amino alcohols ( 2a– d) and diols ( 2e– g) in methylene chloride at room temperature led to the formation of the corresponding fluoro derivatives ( 3a– g) in good yields.
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