Abstract

Active nucleolus-organizer regions (NOR) were identified on chromosomes 3, 4, 5, 7, 8, and 9 in a diploid Chinese hamster primary strain (CHFP-WG). However, they appeared only on one chromosome 4, both chromosomes 5, and the isochromosome for the short arm of chromosome 8 (iso 8p) in an established Chinese hamster line displaying gross chromosomal rearrangements (AK412). Some recognizable NOR sites, exhibiting active NOR in CHFP-WG cells fail to exhibit active NOR in AK412, suggesting that a specific suppression of NOR has occurred in the AK412 cells.

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