Abstract
The role of cytoplasmic ribosomes in protein synthesis has been studied extensively in the past; more recent discoveries suggest ( Noll et al, 1963) that the functional units or protein synthesis are ribosomal aggregates, “ergosomes”, consisting of particles held together by m-RNA. The origin of cytoplasmic ribosomes is a matter of some speculation but a current favorite is that ribosomal RNA is synthesized in the nucleus. The purpose of our report is to present some data which indicate that nuclear ribosomes are labeled earlier than cytoplasmic microsomes during tissue reparation, suggesting nuclear origin of the cytoplasmic microsomes. The studies were carried out on subcellular fractions of infarcted and normal cardiac muscle.
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