Abstract

The continuing strength of nuclear medical diagnosis lies in its ability to depict function and therefore detect physiological alterations in a manner not made available by the more morphologically oriented techniques, such as conventional radiography, computed tomography, and ultrasonography. Developments in the basic science areas of radiotracer technology and instrumentation have moved rapidly from the research laboratory to clinical facilities where they have significantly contributed to the diagnostic armamentarium in medicine and surgery. Three of the more notable areas of particularly intensive investigative efforts during the past two or three years are those of cardiac and gastrointestinal disease and emission tomography. <h3>Cardiac Evaluation</h3> Two major radionuclide approaches to the diagnosis of suspected coronary artery disease have evolved in the past several years.<sup>1,2</sup>These are the use of thallous chloride Tl 201 to evaluate myocardial perfusion<sup>3</sup>and first-pass and multigated radionuclide angiography to evaluate pumping efficiency of the heart.

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