Abstract
The clinical usefulness of nuclear medicine in the preoperative evaluation of epilepsy is highlighted with regard to non-lesional temporal lobe epilepsy, extratemporal epilepsy, bitemporal interictal epileptiform discharges (IEDs) and in dual pathology and cortical dysgenesis. Ictal single photon emission computed tomography (SPECT) shows good sensitivities in the correct lateralization of an electroencephalogram-defined epileptic focus in lesional and, to a lesser extent, non-lesional epilepsy. Positron emission tomography (PET) using 18F-fluorodeoxyglucose or 11C-flumazenil gives a good detection rate of the seizure onset zone in non-lesional cases and extratemporal epilepsy. The investigation of patients with bitemporal IEDs can confirm the existence of bitemporal seizure onset. For patients with a dual pathology or cortical dysgenesis nuclear medicine offers the opportunity to delineate the existence or extension of abnormalities possibly responsible for the seizure disorder.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
