Abstract

Objectives. Green fluorescent protein (GFP) and luciferase bioluminescence have been described for imaging ovarian cancer (OC) xenografts in mice. While tumor location can be assessed with these tools, extent of tumor burden is often difficult to assess due to the margins of light emission. Non-invasive imaging modalities to accurately follow tumor response and recurrence over time in vivo are needed for therapeutic studies in xenograft models. In this study, we sought to explore the utility of magnetic resonance imaging (MRI) in a murine model of ovarian cancer.

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