Abstract

Beta-catenin plays an important role in hair morphogenesis. Previously, nuclear localization of beta-catenin in hair matrix cells was found. Hair and nail have similar properties. However, the expression pattern of beta-catenin in the nail unit has not been reported yet. In this study we evaluated the expression pattern of beta-catenin in human nail unit and a rare nail tumor onychomatricoma.Normal human nail unit was obtained during polydactyly operations and cadavers. Immunohistochemistry for beta-catenin was applied to the sections of normal nail unit and onychomatricoma.

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