Nuclear lamina CRWN proteins regulate chromatin organization, gene expression, and nuclear body formation in plants.

Abstract

The metazoan cell nucleus is physically supported by nuclear lamina structures, which are mainly composed of filamentous protein lamins. CROWDED NUCLEI (CRWNs)/nuclear matrix constituent proteins are considered potential candidates of lamin analogs in plants. CRWNs specifically localize to the nuclear periphery, maintain nuclear morphology, and interact with several inner nuclear membrane proteins. CRWNs also regulate several nuclear events. In this review, I summarize the functions of CRWNs in regulating chromatin organization, gene expression, and nuclear body formation, and provide insights into novel plant nuclear lamina functions and structures.