Nötrofil Lenfosit Oranı Evre 1 Testis Tümörünün Okkült Metastaz Parametrelerinde Bir Markır Olabilir mi?

Abstract

Objective: Neutrophile-Lymphocyte (NLR) and Platelet-Lymphocyte ratio (PLR) comparison is an easy to use and cost-effective method in diagnosis of some cancers and diseases. In this study, we aimed to investigate if NLR / PLR ratio evaluation could be utilized in diagnosis of testicular malignencies especially in early-term with occult metastasis. Methods: A total of 40 patients at stage-I, who have undergone radical inguinal orchiectomy intervention for testicular tumor between 2015 and 2019, and 43 control individuals without any testicular complaints were included in this retrospective study. The relationship between pathological risk factors for occult metastatic disease in Stage-I testicular cancer and NLR-PLR values were investigated. Results: The average age was 30.05 years, and there was no significant difference between the groups by means of age (p=0.150). The NLR and PLR values of the tumor group were prominently higher in the patient group, when compared with the control group (p=0.001 and 0.016, respectively). In the correlation analysis between risk-factors for occult metastatic disease in Stage-I testicular cancer and NLR / PLR, we have found that only a significant correlation was present in terms of tumor size. Conclusion: As a result, we have concluded that NLR increases in all types of testicular tumors. We suggest that higher NLR ratio values can be used as prognostic marker in clinical practice.