Abstract
Aim: In this study, our aim was to compare the effectiveness of combined intraurethral lidocaine and intravenous sedoanalgesia with intraurethral lidocaine alone in patients with undergoing optical internal urethrotomy(OIU) for primary anterior urethral strictures. 
 Materials and methods: A total of 76 patients who underwent OIU with anterior urethral stricture 2-3 cm long were analysed. Patients were divided into two groups. There were 36 patients in group 1 received only intraurethral lidocaine gel (12.5 g,% 2 ) and there were 40 patients in group 2 operated under intraurethral lidocaine gel anesthesia with intravenous sedoanalgesia (1 mg/kg Propofol and 1µg/kg Fentanyl). Anatomic location, length and etiology of the urethral stricture, procedure time, patients’ follow-up and postoperative VAS scores were compared in two groups. 
 Results: There was no significant differences between the two groups in the length of the urethral stricture,age and in the follow-up time. Most of the patients in two groups had iatrogenic as the cause of urethral stricture and the stricture was most commonly located in the bulbar urethra. The mean procedure time and VAS score in group 1 were significantly higher than group 2 (p
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