NPHP3-Related Disease: A Possible Risk Factor for Developing Encapsulating Peritoneal Sclerosis.

Abstract

Encapsulating peritoneal sclerosis (EPS) presents a rare but serious complication of chronic peritoneal dialysis (PD) which is associated with significant morbidity and mortality (Stefanidis CJ et al., Pediatr Nephrol 2014; 29: 2093–2103). In paediatric patients, there are only several previously published studies (Vidal E et al., Nephrol Dial Transplant 2013; 28: 1603–1609; Ekim M et al., Nephrology (Carlton) 2005; 10: 341–343), but the prevalence (8.7 per 1000 patient-years on PD) seems similar as in the adult population (Shroff R et al., Nephrol Dial Transplant 2013; 28: 1908–1914). On the other hand, the general outcome of paediatric patients is better with lower mortality compared to adults (Shroff R et al., Nephrol Dial Transplant 2013; 28: 1908–1914).