Abstract

BackgroundNowcasting approaches enhance the utility of reportable disease data for trend monitoring by correcting for delays, but implementation details affect accuracy.ObjectiveTo support real-time COVID-19 situational awareness, the New York City Department of Health and Mental Hygiene used nowcasting to account for testing and reporting delays. We conducted an evaluation to determine which implementation details would yield the most accurate estimated case counts.MethodsA time-correlated Bayesian approach called Nowcasting by Bayesian Smoothing (NobBS) was applied in real time to line lists of reportable disease surveillance data, accounting for the delay from diagnosis to reporting and the shape of the epidemic curve. We retrospectively evaluated nowcasting performance for confirmed case counts among residents diagnosed during the period from March to May 2020, a period when the median reporting delay was 2 days.ResultsNowcasts with a 2-week moving window and a negative binomial distribution had lower mean absolute error, lower relative root mean square error, and higher 95% prediction interval coverage than nowcasts conducted with a 3-week moving window or with a Poisson distribution. Nowcasts conducted toward the end of the week outperformed nowcasts performed earlier in the week, given fewer patients diagnosed on weekends and lack of day-of-week adjustments. When estimating case counts for weekdays only, metrics were similar across days when the nowcasts were conducted, with Mondays having the lowest mean absolute error of 183 cases in the context of an average daily weekday case count of 2914.ConclusionsNowcasting using NobBS can effectively support COVID-19 trend monitoring. Accounting for overdispersion, shortening the moving window, and suppressing diagnoses on weekends—when fewer patients submitted specimens for testing—improved the accuracy of estimated case counts. Nowcasting ensured that recent decreases in observed case counts were not overinterpreted as true declines and supported officials in anticipating the magnitude and timing of hospitalizations and deaths and allocating resources geographically.

Highlights

  • MethodsTimeliness is a key attribute of surveillance systems for reportable infectious diseases [1,2]

  • Researchers have assessed the potential to nowcast COVID-19 cases and deaths using Google Trends data available in near-real time [11], and have applied a range of modeling approaches that leverage reporting delays to estimate the number of not-yet-reported cases and deaths [12,13]

  • We describe the use and evaluation of a time-correlated Bayesian nowcasting approach at the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) during the first epidemic wave of COVID-19 to support real-time situational awareness and resource allocation

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Summary

Introduction

MethodsTimeliness is a key attribute of surveillance systems for reportable infectious diseases [1,2]. Monitoring prediagnostic data sources (eg, emergency department syndromic surveillance [6], internet searches and social media [7], participatory surveillance of self-reported symptoms [8], smart thermometers [9], etc) can improve timeliness at the expense of specificity, such as an inability to distinguish increases in respiratory illness attributable to influenza from COVID-19. Another approach that preserves specificity when monitoring COVID-19 disease trends is to leverage partially reported disease data, formally accounting for data lags. Nowcasting approaches enhance the utility of reportable disease data for trend monitoring by correcting for delays, but implementation details affect accuracy

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