Abstract
Two methods for investigating the effects of mechanical strain on the structure of biological membranes are proposed and illustrated in the case of the erythrocytic membrane. Firstly, we show that the diffusion limiting current measured at a rotating disc electrode for a biological suspension allows one to follow the variation of the adhesion of the cells to the wall with the hydrodynamic conditions, provided that the results be interpreted in the framework of partially blocked electrodes. Secondly, we propose an entirely novel method, which consists in following in a Couette flow, the variation of the light intensity of a fluorescent probe (for instance a membrane potential probe) with the shear rate. Original results concerning the erythrocytic membrane are provided both under stationary and non-stationary conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
