Novel therapy of prostate cancer employing a combination of viral-based immunotherapy and a small molecule BH3 mimetic

Siddik Sarkar,Anjan Pradhan,Swadesh K Das,Luni Emdad,Devanand Sarkar,Maurizio Pellecchia,Paul B Fisher

doi:10.1080/2162402x.2015.1078059

Novel therapy of prostate cancer employing a combination of viral-based immunotherapy and a small molecule BH3 mimetic

Siddik Sarkar, Anjan Pradhan + Show 5 more

Open Access

https://doi.org/10.1080/2162402x.2015.1078059

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Journal: OncoImmunology	Publication Date: Sep 4, 2015
Citations: 7

Affiliation: Virginia Commonwealth University, Discovery Institute

#Metastatic Hormone Refractory Prostate Cancer #Cancer Terminator Virus + Show 8 more

Abstract
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Abstract

ABSTRACTCancer-selective viral replication and delivery of a therapeutic immunomodulating, cancer-selective killing cytokine (mda-7/IL-24) by means of a new Cancer Terminator Virus (CTV) combined with a small molecule BH3 mimetic holds promise for treating both primary and metastatic hormone refractory prostate cancer (CaP).

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