Abstract
Novel sulfonamide organocatalysts were prepared from chiral Betti base and various sulfonyl chlorides, and applied to the asymmetric hetero-Diels-Alder reaction of ethyl glyoxylate with Danishefsky's diene. The sulfonamides exhibited catalytic activity as hydrogen bond donor. In particular, sulfonamide 3g showed highest catalytic performance for the reaction. Sulfonamide 3g catalyzed asymmetric reaction followed by treatment with TFA obtained corresponding 6-substituted 2,3-dihydropyran-4-ones in moderate yield and enantioselectivity.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
