Abstract
Abstract A novel seco-pregnane steroid bearing an oxygen-bridged structure and two new sesquiterpene lactones—namely, sausinone (1),14-oxidized mokko lactone (2), and (1R, 5R, 6R, 7R, 8S, 11S)-11,13-dihydrodehydrocostuslactone-8-O-6′-2″ (Z)-butenoyl-β-D-glucopy-ranoside (3)—along with 12 known compounds (4–15) were isolated from Saussurea involucrata. Notably, compounds 12–15 were isolated from this plant for the first time. Their structures were mainly established by one- and two-dimensional nuclear magnetic resonance analysis.
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