Abstract
Background and Aims : We have discovered that PCSK6 modulates vascular smooth muscle cell remodeling in atherosclerosis and participates in plaque (in)stability via activation of matrix metalloproteinases, various mitogens and growth factors. In addition, PCSK6 processes two triglyceride lipase family members, endothelial lipase and lipoprotein lipase (LPL) with a possible impact on plasma lipoprotein levels and the adipose tissue. We aimed to investigate the role of PCSK6 in the adipose tissue related lipid metabolism using Pcsk6-/- mice.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
