Abstract
To the Editor: Avian influenza A(H5N6) influenza viruses have circulated among poultry in southern (Jiangxi, Guangdong) and western (Sichuan) provinces of China since 2013 (1,2). In 2014, outbreaks of H5N6 virus infection occurred among poultry in China, Laos, and Vietnam (1). In April 2014, the first case of highly pathogenic H5N6 infection among humans was detected in Sichuan Province (3); the second case was detected on December 3, 2014, in Guangdong Province (4). In December 2015, 4 humans in Guangdong Province were infected with H5N6 influenza (5,6).
Highlights
The rapid increase in MenW cases among infants, most recently (2014–15), is cause for concern, and the contemporaneous introduction of MenB vaccine into the national immunization schedule is timely
To study the genetic basis of continuing human infections with this avian influenza subtype, we sequenced the complete genomes of 2 of the 4 human H5N6 isolates obtained in December 2015 in Guangdong Province
We compared these sequences with those of 1 H6N6 and 8 H5N6 influenza viruses isolated from birds in live poultry markets in this region during 2013–2015 and other published genomes of H5, H6N6, and H9N2 avian influenza viruses
Summary
The rapid increase in MenW cases among infants, most recently (2014–15), is cause for concern, and the contemporaneous introduction of MenB vaccine into the national immunization schedule is timely. Novel Reassortant Avian Influenza A(H5N6) Viruses in Humans, Guangdong, China, 2015 Yong-Yi Shen,1 Chang-Wen Ke,1 Qian Li,1 Run-Yu Yuan, Dan Xiang, Wei-Xin Jia, Yun-Di Yu, Lu Liu, Can Huang, Wen-Bao Qi, Reina Sikkema, Jie Wu, Marion Koopmans, Ming Liao
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