Abstract
An accurate diagnosis of osteosarcoma of the jaws (OS) is determined by proper documentation and interpretation of clinical symptoms, radiologic findings, meticulous histologic survey, and a characteristic growth pattern. The characteristics of high-grade OS include a chief complaint of swelling/pain, a “fluffy” radiologic appearance with or without corticomedullary involvement, osteoblasts as the predominant cell type on histologic examination, and a highly aggressive growth pattern arising from the periosteal tissue. 1 Okada K. Unni K.K. Swee R.G. Sim F.H. High grade surface osteosarcoma: A clinicopathologic study of 46 cases. Cancer. 1999; 85: 1044 Crossref PubMed Scopus (78) Google Scholar , 2 Wold L.E. Unni K.K. Beabout J.W. Pritchard D.J. High-grade surface osteosarcomas. Am J Surg Pathol. 1984; 8: 181 Crossref PubMed Scopus (81) Google Scholar OSs of the mandible and maxilla are collectively known as gnathic osteosarcomas (GOSs) and usually exhibit long-standing pain or swelling. Emphasis on multidisciplinary oncologic, surgical, and prosthetic treatment planning of GOSs improves the treatment outcome and long-term prognosis. The treatment of GOSs, especially in the mandible, requires careful consideration of adjacent bone, soft tissue, surrounding perioral musculature, teeth, interocclusal relationships, and facial aesthetics.
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