Abstract

A cluster of severe acute respiratory syndrome coronavirus 2 infections in Danang, Vietnam, began July 25, 2020, and resulted in 551 confirmed cases and 35 deaths as of February 2021. We analyzed 26 sequences from this cluster and identified a novel shared mutation in nonstructural protein 9, suggesting a single introduction into Vietnam.

Highlights

  • Hoang Vu Mai Phuong,1 Trinh Son Tung,1 Ung Thi Hong Trang, Nguyen Le Khanh Hang, Nguyen Vu Son, Pham thi Hien, Le thi Thanh, Vuong Duc Cuong, Ton That Thanh, Nguyen thi Thanh Nhan, Tran Nhu Duong, Ngu Duy Nghia, Tran Anh Tu, Marc Choisy, Maia A

  • After 99 days without community transmission, a cluster of SARSCoV-2 infections of unknown origin was detected in Danang; it was found in Danang General Hospital on July 25 in a 57-year-old male patient (DN001) experiencing pneumonia who had no travel history

  • We describe the molecular epidemiology of this cluster

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Summary

Introduction

Hoang Vu Mai Phuong,1 Trinh Son Tung,1 Ung Thi Hong Trang, Nguyen Le Khanh Hang, Nguyen Vu Son, Pham thi Hien, Le thi Thanh, Vuong Duc Cuong, Ton That Thanh, Nguyen thi Thanh Nhan, Tran Nhu Duong, Ngu Duy Nghia, Tran Anh Tu, Marc Choisy, Maia A. Author affiliations: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam (H.V.M. Phuong, U.T.H. Trang, N.L.K. Hang, N.V. Son, P. thi Hien, L. thi Thanh, V.D. Cuong, T.N. Duong, N.D. Nghia, T.A. Tu, D.D. Anh, L.Q. Mai); Oxford University Clinical Research Unit, Hanoi (T.S. Tung, H.R. van Doorn); Centre for Disease Control and Prevention, Danang, Vietnam A cluster of severe acute respiratory syndrome coronavirus 2 infections in Danang, Vietnam, began July 25, 2020, and resulted in 551 confirmed cases and 35 deaths as of February 2021.

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