Abstract

Background and Study Aims. Most available jumbo cup forceps require a 3.7 mm biopsy channel, necessitating the use of standard-sized colonoscope. A newer jumbo forceps (Radial Jaw 4 Jumbo Biopsy Forceps [RJ4]) fits within a 3.2 mm biopsy channel, allowing use with a pediatric colonoscope. To assure the RJ4 did not alter biopsy adequacy, we compared the size and quality of specimens to a historical jumbo cup forceps (Radial Jaw 3 Max Capacity Biopsy Forceps, [RJ3 MC]). Patients and Methods. A retrospective comparative study of biopsies taken with either forceps. Biopsies were compared for diameter, depth, crush artifact, and acceptability for diagnosis. Results. 333 specimens were taken with RJ4 and 335 specimens with the RJ3 MC. Mean sample diameter was 4.45 mm and 4.55 mm for the RJ4 and RJ3 MC (P = 0.41). Mean depth of biopsies with the RJ4 was greater (P < 0.01). Conclusions. Biopsies from the RJ4 are similar in size and quality to biopsies from the RJ3 MC. The RJ4 has the advantage of fitting in a smaller biopsy channel.

Highlights

  • Jumbo cup biopsy forceps were developed to maximize the surface area of mucosal biopsies and thereby increase the diagnostic yield of the sample

  • While standard clinical practice has included the use of jumbo cup forceps for inflammatory bowel disease (IBD) surveillance biopsies, this forceps requires the use of an adult colonoscope because a 3.7 mm working biopsy channel is necessary to accommodate the typical jumbo cup biopsy forceps

  • The goal of the present study was to compare the size and the quality of biopsies taken with the new Radial Jaw 4 Jumbo Biopsy Forceps (RJ4) forceps to those taken with a historical jumbo cup biopsy forceps

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Summary

Introduction

Jumbo cup biopsy forceps were developed to maximize the surface area of mucosal biopsies and thereby increase the diagnostic yield of the sample. Most currently available pediatric colonoscopes have a 3.2 mm working channel which is not of sufficient diameter to allow passage of the standard jumbo cup biopsy forceps. A new large diameter biopsy forceps, the Radial Jaw 4 Jumbo Biopsy Forceps (RJ4) [Boston Scientific, Inc., Boston, Mass, USA] has been developed to fit within the working channel of a pediatric colonoscope. The goal of the present study was to compare the size and the quality of biopsies taken with the new RJ4 forceps to those taken with a historical jumbo cup biopsy forceps. A newer jumbo forceps (Radial Jaw 4 Jumbo Biopsy Forceps [RJ4]) fits within a 3.2 mm biopsy channel, allowing use with a pediatric colonoscope. To assure the RJ4 did not alter biopsy adequacy, we compared the size and quality of specimens to a historical jumbo cup forceps (Radial Jaw 3 Max Capacity Biopsy Forceps, [RJ3 MC]). The RJ4 has the advantage of fitting in a smaller biopsy channel

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