Abstract

Melanie J. Coathup, BSc, PhD, Niall Kent, BSc, PhD, Robert Hill, BSc, MSc, PhD, DIC, Roberta De Godoy, DVM, MSc, PhD, Wen-Yu Quak, BSc, Lyris Onwordi, MBBS, MSc, Gordon W. Blunn, Bsc, PhD. University College London, Division of Surgery and Interventional Science, Institute of Orthopaedics and Musculoskeletal Science, Stanmore, Middlesex, United Kingdom, Barts and The London School of Medicine and Dentistry, Queen Mary University, London, United Kingdom.

Highlights

  • Calcium phosphate cements (CPCs) have been widely used as an alternative to biological grafts as they present excellent biocompatibility and osteoconductive properties

  • Studies have shown that octacalcium phosphate (OCP) is more soluble when compared with calcium hydroxyapatite, and that the resorption of OCP is followed by new bone formation

  • Novel work previously performed by the authors, has successfully introduced Bioactive glasses (BGs) into (i) hydroxyapatite, (ii) octacalcium phosphate and (iii) fluorohydroxyapatite cements without compromising the setting time

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Summary

Introduction

Calcium phosphate cements (CPCs) have been widely used as an alternative to biological grafts as they present excellent biocompatibility and osteoconductive properties. BSc, PhD1, Niall Kent, BSc, PhD2, Robert Hill, BSc, MSc, PhD, DIC2, Roberta De Godoy, DVM, MSc, PhD1, Wen-Yu Quak, BSc1, Lyris Onwordi, MBBS, MSc1, Gordon W. Studies have shown that octacalcium phosphate (OCP) is more soluble when compared with calcium hydroxyapatite, and that the resorption of OCP is followed by new bone formation.

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