Abstract
In January 2019, a human seasonal reassortant influenza A(H1N2) virus with a novel 7:1 genetic constellation was identified in a 68-year-old female patient with suspected pneumonia. The virus harboured A(H3N2) neuraminidase and remaining genes from A(H1N1)pdm09. The patient recovered after severe illness. No additional cases have been detected. This is the second identified A(H1N2) seasonal reassortant in a human in Europe within 1 year; a previous case was detected in the Netherlands in March 2018.
Highlights
Article submitted on 15 Feb 2019 / accepted on 25 Feb 2019 / published on 28 Feb 2019 In January 2019, a human seasonal reassortant influenza A(H1N2) virus with a novel 7:1 genetic constellation was identified in a 68-year-old female patient with suspected pneumonia
Influenza surveillance in Sweden In Sweden, surveillance of influenza is conducted at the Public Health Agency of Sweden (PHAS), which acts as the National Influenza Centre
While co-infections with seasonal A(H1N1) and A(H3N2) influenza strains are not unusual [4,5,6,7], only a few studies have described reassortant viruses as a consequence of such co-infections [8,9,10]. This suggests that reassortment is a rare occurrence and that reassorted A(H1N2)-viruses do not spread between humans [11], with the exception of A(H1N2) reassortant viruses circulating in 1988/89 in China [12,13] and worldwide between 2001 and 2003 [14]
Summary
Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019. Citation style for this article: Wiman Åsa, Enkirch Theresa, Carnahan AnnaSara, Böttiger Blenda, Hagey Tove Samuelsson, Hagstam Per, Fält Rosmarie, Brytting Mia. Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019. In January 2019, a human seasonal reassortant influenza A(H1N2) virus with a novel 7:1 genetic constellation was identified in a 68-year-old female patient with suspected pneumonia. As part of Swedish national influenza surveillance, a seasonal reassortant influenza A(H1N2) virus with a novel genetic constellation was identified. This is the second detected seasonal A(H1N2) reassortant in a human in Europe within 1 year. We describe the detection of the virus, its genetic characteristics and follow-up investigations
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
