Abstract
Introduction: Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars. We have previously published clinical and histological results from the treatment of 8 patients with active acne and acne related scarring using a fractional RF device. Evidence of safety and efficacy was demonstrated, including long term follow-up clinical results from 4 patients, up to two years post last fractional treatment. In the current article we present histology evidence of acne scar skin renewal 3.5 years post treatment. Methods: Skin biopsies from acne scars in a concealed facial area were taken before, after four treatments and at 3.5 years after the last fractional treatment. Biopsies were examined with standard hematoxylin and eosin (H&E) stain, as well as Verhoeff’s Van Gieson (VVG) and Shikata stains for elastic fibers. Results: Histological findings demonstrate regeneration of elastic fibers and reduction of the dermal fibrosis. Scar depth of Patient #2 was reduced by 80% in the corresponding follow-up period. Conclusion: The long-term histological results further support the previously published findings that fractional RF is a safe and effective treatment for acne related scars.
Highlights
Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars
Biopsies were examined with standard hematoxylin and eosin (H&E) stain, as well as Verhoeff’s Van Gieson (VVG) and Shikata stains for elastic fibers
In previously published articles we demonstrated our experience with an fractional RF (FRF) device in the treatment of eight patients with active acne and acne-related scarring [8]
Summary
Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars. We have previously published clinical and histological results from the treatment of 8 patients with active acne and acne related scarring using a fractional RF device. Evidence of safety and efficacy was demonstrated, including long term follow-up clinical results from 4 patients, up to two years post last fractional treatment. In the current article we present histology evidence of acne scar skin renewal 3.5 years post treatment. Methods: Skin biopsies from acne scars in a concealed facial area were taken before, after four treatments and at 3.5 years after the last fractional treatment. Conclusion: The long-term histological results further support the previously published findings that fractional RF is a safe and effective treatment for acne related scars. Recontouring of atrophic facial scars with CO2 and Er:YAG lasers has become popular over the last decade [4] [5]; due to the extended post-laser recovery period and the potential risks, especially to candidates with dark skin type, patients have been less willing to undergo ablative laser skin resurfacing [6]
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