Novel Hantavirus Sequences in Shrew, Guinea

Boris Klempa,Helga Meisel,Brita Auste,Vladimir Aniskin,Lamine Koivogui,Emilie Lecompte,Patrick Barrière,Detlev H Krüger,Elisabeth Fichet-Calvet,Jan Ter Meulen

doi:10.3201/eid1303.061198

Abstract

Novel Hantavirus Sequences in Shrew, Guinea

Highlights

During a study of rodentborne hemorrhagic fever viruses performed in Guinea in 2002–2004, 32 shrews of the genus Crocidura were collected and screened for hantavirus RNA by reverse transcription–PCR [5]
Maximum likelihood phylogenetic analysis of hantaviruses showing the phylogenetic placement of Tan826 (Tanganya virus, indicated by arrow) based on partial L segment nucleotide (A) and amino acid (B) sequences and partial S segment amino acid sequences (C); GenBank accession nos
A partial S segment sequence (442 nt, 147 aa of the putative nucleoprotein) was determined to compare Tan826 directly with the shrew-associated Thottapalayam virus (TPMV)

Summary

Introduction

Hantaviruses have been divided into 3 major groups that resemble 3 subfamilies of their natural hosts (Figure, panel A). We report the recovery of hantavirus RNA of a novel sequence from a shrew, collected in Guinea, West Africa. During a study of rodentborne hemorrhagic fever viruses performed in Guinea in 2002–2004, 32 shrews of the genus Crocidura were collected and screened for hantavirus RNA by reverse transcription–PCR [5].

Results

Conclusion