Abstract
Several studies have demonstrated that irregularities in eye movements represent an important indicator to diagnose diseases affecting the central nervous system. In fact, abnormal horizontal and vertical eye movements play an important role in measuring the progress of neurodegenerative diseases. Electro-oculography (EOG) is a widespread technique that monitors the horizontal and vertical eye movements in response to a visual stimulation pattern. These visual stimuli require stimulus-response synchronization, low latency, and a real-time response. In this work, a novel system based on a Field-Programmable Gate Array (FPGA) is designed to address hundreds of LEDs for the generation of multiple visual stimulus signals and for EOG acquisition. Our evaluation demonstrates that the proposed system enhances the accuracy of the signals generated, showing excellent results in the stimulus-response synchronism and quality of the stimuli waveform.
Highlights
Eye movement analysis has vital importance in the diagnosis of illnesses related to the central nervous system (CNS)
Regarding the design of a visual stimulator as part of an electrooculographic system for the diagnosis of neurodegenerative diseases, we only found the work of Perez Guzman [15]
CM are allocated in the Field-Programmable Gate Array (FPGA), where the visual stimuli and the processing of the acquired EOG is performed
Summary
Eye movement analysis has vital importance in the diagnosis of illnesses related to the central nervous system (CNS). For detecting potential neurodegenerative diseases using EOG, there are different types of visual stimuli Analyzing their principles and characteristics is important to understand the architecture of the proposed system. The LED panels are the counterpart of the previous ones, and they have an acceptable resolution, but at lower costs and with great portability. They do not cause significant electromagnetic interference on the EOG signals [31], and due to this nearly instantaneous switching response [32], they are ideal for complex displays and finely controlled temporal patterns of stimulation
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