Abstract
The deer mouse (Peromyscus maniculatus) is the primary reservoir for Sin Nombre virus (SNV) in the western United States. Rodent surveillance for hantavirus in Death Valley National Park, California, USA, revealed cactus mice (P. eremicus) as a possible focal reservoir for SNV in this location. We identified SNV antibodies in 40% of cactus mice sampled.
Highlights
Hantaviruses constitute a worldwide group of predominantly rodentborne zoonotic pathogens, some of which have emerged as distinctive human health hazards
Phylogenetic tree of Gn glycoprotein sequences comparing hantaviruses sampled from 48 Peromyscus eremicus and 1 P. maniculatus (DEVA 10 022) mice collected in Death Valley National Park, California, USA
The P. maniculatus deer mouse is recognized as the primary reservoir for Sin Nombre virus (SNV) in the western United States
Summary
Hantaviruses constitute a worldwide group of predominantly rodentborne zoonotic pathogens, some of which have emerged as distinctive human health hazards. In California, SNV-seropositive rodents typically have not been found to exceed the average P. maniculatus infection prevalence of ≈14%, infection prevalence estimates have slightly exceeded 14% among certain populations of R. megalotis mice [3,7]. We conducted a survey in Death Valley National Park, California, USA, to document the presence and estimate the infection prevalence of hantavirus in rodents living in and around buildings within select developed areas of the park.
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