Abstract
Antioxidant and antiglycating activities of 2,6-di-tert-butyl-4-[N-(4-pyridyl)iminomethyl]phenol (1), 2,6-di-tert-butyl-4-[N-(3-pyridylmethyl)-iminomethyl]phenol (2) and N-(3,5-di-tert-butyl-4-hydroxyphenyl)iminomethylferrocene (3) have been studied. Antioxidant activity of 2,6-di-tert-butylphenol bearing ferrocenyl moiety was shown to be sufficiently higher than that of the compounds 1 and 2. Based on the data obtained in comparison with aminoguanidine which is an effective protein glycation inhibitor it was established that the introduction of ferrocenyl moiety into 2,6-di-tert-butylphenol results in a dramatic increase in the antiglycating activity exceeding that for aminoguanidine.
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