Abstract
Background: Silent uncontrolled hypertension can cause major organ damage.
 Case presentation: A 42-year-old hypertensive male used fenofibrate to lower his triglyceride levels; however, the investigation revealed that it caused a significant increase in the desire and ingestion of greasy food items which caused fluctuating high blood pressure. Correction of the dietary regimen and a modification in the usual recommended drug dose led to a significant positive development of the medical case. Specifically, it was successful in adjusting the systolic and diastolic blood pressure components and blood test parameters, and was effective in correcting the glucose criteria back to the acceptable standard range.
 Conclusion: This is the first evidence in the literature on a poorly controlled hypertension case associated indirectly with fenofibrate.
Highlights
The increase in blood pressure, a silent killer, is one of the most common long-lasting illnesses among patients in major health care programs 1
Secondary hypertension might be due to some drugs, kidney disorders, endocrine diseases, and cancer
With time the blood pressure and lipids improved slightly and the strong headache episodes were not as common anymore. He continued these medications but after six months from the first episode he experienced, there was an onset of similar symptoms including infuriating headache, high blood pressure, and high plasma lipids, regardless of his commitment to taking the exact daily drug dose which was prescribed
Summary
The increase in blood pressure, a silent killer, is one of the most common long-lasting illnesses among patients in major health care programs 1. He was given oral medications: amlodipine (5 mg/day in the morning), fenofibrate (200 mg/day in the morning), and simvastatin (20 mg/day at night) As he indicated, with time the blood pressure and lipids improved slightly and the strong headache episodes were not as common anymore. He continued these medications but after six months from the first episode he experienced, there was an onset of similar symptoms including infuriating headache, high blood pressure, and high plasma lipids, regardless of his commitment to taking the exact daily drug dose which was prescribed His medical doctor instructed him to continue to take the identical doses of simvastatin and fenofibrate but to change the hypertension prescription to a mixture of three medications (commercially accessible as one pill) which included amlodipine (5 mg), hydrochlorothiazide (12.5 mg), and olmesartan medoxomil (40 mg). The patient indicated that his strong desire toward fatty food items decreased significantly and there was not any noticeable challenge in following the new regimen
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