Novel Fe3O4@metal-organic framework@polymer core-shell-shell nanospheres for fast extraction and specific preconcentration of nine organophosphorus pesticides from complex matrices

Abstract

Herein, a novel core-shell-shell magnetic nanosphere denoted as Fe3O4@ZIF-8@polymer was fabricated by sequential in situ self-assembly and precipitation polymerization for effective magnetic solid-phase extraction of nine organophosphorus pesticides (OPPs) from river water, pear, and cabbage samples. The integrated Fe3O4@ZIF-8@polymer featured convenient magnetic separation property and excellent multi-target binding ability. More importantly, the functional polymer coating greatly improved the extraction performance of Fe3O4@ZIF-8 for OPPs, thus facilitating the simultaneous determination of trace OPP residues in real samples. The developed MPSE-LC-MS/MS method exhibited good linearity (R2 ≥ 0.9991) over the concentration range of 0.2–200 µg L−1, low limits of detection of 0.0002–0.005 μg L−1 for river water and 0.006–0.185 μg kg−1 for pear and cabbage, satisfactory precision with relative standard deviations ≤ 9.7% and accuracy with recoveries of 69.5–94.3%. These results highlight that the combination of polymers with MOFs has great potential to fabricate excellent adsorbents for high-throughput analysis of various contaminants in complex matrices.