Abstract
In this work, Poly(lactic acid) (PLA)/poly(butylene carbonate) (PBC)/graphene oxide (GO) nanofiber membranes with different content GO were successfully prepared by electrospinning. The structural and physical characteristics of the membranes were investigated by scanning electron microscopy (SEM), Differential Scanning Calorimeter (DSC), contact angle test, Fourier Transform Infrared Spectroscopy (FT-IR), agar diffusion method. SEM observations revealed a fine dispersion of GO in the nanofiber matrices. FT-IR spectra result showed that the GO, PBC and PLA mixed well in the PLA/PBC/GO films. The antibacterial properties of nanofiber membranes were also investigated. The results indicated that the antimicrobial activities of PLA/PBC/GO composite nanofibrous films were much higher than that of pure PLA/PBC nanofibrous films. Meanwhile, the antimicrobial activity against S.aureus was also slightly higher than E. coli.
Highlights
In recent years, electrospinning technology has been widely used in the fields of battery electrode materials,1 sensors,2 tissue engineering scaffold,3 drug carrier4 and efficient filtration materials5 that depend on controllable fiber diameter, high specific surface area, high porosity and low cost
The results indicated that the antimicrobial activities of Poly(lactic acid) (PLA)/poly(butylene carbonate) (PBC)/Graphene oxide (GO) composite nanofibrous films were much higher than that of pure PLA/PBC nanofibrous films
The results show that the pure PLA/PBC nanofibrous membranes have some antimicrobial activity
Summary
In recent years, electrospinning technology has been widely used in the fields of battery electrode materials, sensors, tissue engineering scaffold, drug carrier and efficient filtration materials that depend on controllable fiber diameter, high specific surface area, high porosity and low cost. With the development of research, more and more materials including high polymers, inorganic fillers, biomacromolecule and so on were used in the preparation of nano fibers by electrospinning.. The nanofibers scitation.org/journal/adv prepared with PLA are widely used in biomedicine, such as tissue engineering scaffolds, drug carriers, wound healing bandages, and they are a kind of environmentally friendly polymer material with wide application prospects.. PBC has excellent tensile strength, biocompatibility and hydrophilicity via the transesterification method.. PBC has excellent tensile strength, biocompatibility and hydrophilicity via the transesterification method.12 These characteristics make PBC regard as one of the most promising environment-friendly biodegradable plastics.. GO is one of the important derivatives of graphene, which has many oxygen-containing functional groups and layered structures. GO are used in the fields of battery, tissue engineering and cancer treatment due to the excellent electrical conductivity, high specific surface area and biological properties.
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